Bioinformatics and Functional Genomics, 3ed

Jonathan Pevsner

ISBN: 9788126567683

1160 pages

Exclusively distributed by CBS Publishers & Distributors



Bioinformatics and Functional Genomics, Third Edition is the latest revision of this bestselling and indispensible text book. Thoroughly updated to encompass the latest advances in the field the book retains its broad and accessible approach. Divided into three parts the book deals first with bioinformatics, the use of computer databases and computer algorithms in the study of proteins and genes. The first section includes sequence alignment, database searches and phylogeny. The second section of the book focuses on functional genomics and includes approaches such as gene expression profiling and proteomics that are used to study cellular function. The final part of the book deals with genomics which is the study of the collection of DNA that comprises an organism, using the tools of bioinformatics.

Part I Analyzing DNA RNA and Protein Sequences

1 Introduction  

2 Access to Sequence Data and Related Information

3 Pairwise Sequence Alignment

4 Basic Local Alignment Search Tool (BLAST)

5 Advanced Database Searching

6 Multiple Sequence Alignment

7 Molecular Phylogeny and Evolution


Part II Genomewide Analysis of DNA RNA and Protein

8 DNA: The Eukaryotic Chromosome

9 Analysis of Next-Generation Sequence Data

10 Bioinformatic Approaches to Ribonucleic Acid (RNA)

11 Gene Expression: Microarray and RNA-seq Data Analysis

12 Protein Analysis and Proteomics

13 Protein Structure

14 Functional Genomics


Part III Genome Analysis

15 Genomes Across the Tree of Life

16 Completed Genomes: Viruses

17 Completed Genomes: Bacteria and Archaea

18 Eukaryotic Genomes: Fungi

19 Eukaryotic Genomes: From Parasites to Primates

20 Human Genome

21 Human Disease



Self-Test Quiz: Solutions

Author Index

Subject Index