eBook - Drug Disposition and Pharmacokinetics, 2ed: Principles and Applications for Medicine, Toxicology and Biotechnology
Available Exclusively as an eBook | Part of the AI Collection | Only for Institutional Purchase | Publication Year: 2022
Description
This fully revised 2nd edition provides a comprehensive discussion on drug disposition and pharmacokinetics, covering drug absorption, distribution, metabolism, and excretion. It includes new topics such as monoclonal antibodies, stereochemistry, DMPK in non-human species, and AI in drug development, ideal for professionals and researchers in medicine, toxicology, and biotechnology.
Table of Contents
Preface
Setting the Scene: Concepts
Nature of Drugs and Quality of Results
Drug Disposition and Fate
Pharmacokinetic Modelling
Pharmacokinetics of Metabolism and Excretion
Quantitative Pharmacological Relationships
Predictive Pharmacokinetics
Disposition of Peptides and Other Biological Molecules
Monoclonal Antibodies
Drug Metabolism and Pharmacokinetics in Veterinary Sciences
Factors Affecting Plasma Concentrations, Pharmacogenetics
Pharmacogenomics and Precision Medicine
Effects of Sex and Pregnancy on Drug Disposition and Pharmacokinetics
Developmental Pharmacology and Age-related Phenomena
Effects of Disease on Drug Disposition and Pharmacokinetics
Role of Stereochemistry in Drug Disposition and Pharmacokinetics
Drug Metabolism and Pharmacokinetics in Drug Interactions and Toxicity
Drug Monitoring in Therapeutics
From Antiquity to the Age of Artificial Intelligence: Reflections on the Past
Present and Future of Drug Disposition and Pharmacokinetics